Description

tert-Butyl 2,7-Diazaspiro[4.5]Decane-2-Carboxylate Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced pharmacological profiles. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the synthesis of linker components for bifunctional molecules designed for targeted protein degradation.
• CNS Drug Discovery: Employed in the research and development of therapeutics targeting neurological disorders.
• Oncology Research: Utilized as a building block for novel small-molecule inhibitors and targeted cancer therapies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2,7-Diazaspiro[4.5]Decane-2-Carboxylate Hemioxalate
CAS No.	1523606-54-3
Molecular Formula	C13H24N2O2 • ½C2H2O4
Molecular Weight	Contact for details
Synonyms	2,7-Diazaspiro[4.5]decane-2-carboxylic acid, 1,1-dimethylethyl ester, hemioxalate; tert-Butyl 2,7-diazaspiro[4.5]decane-2-carboxylate oxalate (1:0.5); 2-tert-Butoxycarbonyl-2,7-diazaspiro[4.5]decane hemioxalate; Boc-2,7-diazaspiro[4.5]decane hemioxalate; 2-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.5]decane hemioxalate; 2,7-Diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester hemioxalate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,7-Diazaspiro[4.5]Decane-2-Carboxylate Hemioxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply under cGMP guidelines for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.