Description

4-(Azetidin-3-Yl)-2,2-Dimethylmorpholine Ditrifluoroacetate is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining azetidine and morpholine motifs. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable source of complex building blocks for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes under GMP conditions.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for target validation and mechanistic studies.

Basic Information

Item	Detail
Product Name	4-(Azetidin-3-Yl)-2,2-Dimethylmorpholine Ditrifluoroacetate
CAS No.	1523606-35-0
Molecular Formula	C13H21F6N3O5
Molecular Weight	413.32 g/mol
Synonyms	2,2-Dimethyl-4-(azetidin-3-yl)morpholine ditrifluoroacetate; 4-(Azetidin-3-yl)-2,2-dimethylmorpholine bis(trifluoroacetate); 2,2-Dimethyl-4-(azetidin-3-yl)morpholine bis(trifluoroacetate); 4-(3-Azetidinyl)-2,2-dimethylmorpholine ditrifluoroacetate; 2,2-Dimethyl-4-(azetidin-3-yl)-morpholine ditrifluoroacetate salt; 1523606-35-0; Azetidine-morpholine derivative ditrifluoroacetate salt
EINECS	Contact for details

Quality Control

Our 4-(Azetidin-3-Yl)-2,2-Dimethylmorpholine Ditrifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.