Description

(2S)-1,4-Dioxane-2-Methanamine Hydrochloride is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized dioxane scaffold, which is crucial for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs or novel molecular architectures.
• Material Science Research: Potential building block for designing functional polymers or supramolecular systems with specific chiral properties.

Basic Information

Product Name	(2S)-1,4-Dioxane-2-Methanamine Hydrochloride
CAS No.	1523541-96-9
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	(2S)-1,4-Dioxan-2-ylmethanamine hydrochloride; (S)-1,4-Dioxane-2-methanamine HCl; (S)-2-(Aminomethyl)-1,4-dioxane hydrochloride; (S)-1,4-Dioxan-2-ylmethylamine hydrochloride; 1,4-Dioxane-2-methanamine, (2S)-, hydrochloride; (S)-C-1,4-Dioxan-2-yl-methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (2S)-1,4-Dioxane-2-Methanamine Hydrochloride is manufactured under strict quality control protocols to ensure high chemical and chiral purity, essential for sensitive synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.