Description

6-Methoxyspiro[Cyclopropane-1,3-Indoline] is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic and cyclopropane-fused indoline scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules with potential applications in drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in developing new therapeutics, particularly for central nervous system (CNS) targets and other disease areas where complex heterocyclic architectures are explored.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Its structural motif is relevant for exploring potential treatments for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological processes and protein function.
• Agrochemical Research: May be investigated as an intermediate for developing new active ingredients with novel modes of action.
• Academic Synthesis: Employed in university and institutional labs for methodological development and the study of spirocyclic compound chemistry.

Basic Information

Item	Detail
Product Name	6-Methoxyspiro[Cyclopropane-1,3-Indoline]
CAS No.	1523068-91-8
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	6-Methoxyspiro[cyclopropane-1,3'-indoline]; 6-Methoxy-1'-azaspiro[cyclopropane-1,3'-indoline]; 6-Methoxy-1-azaspiro[2.3]hex-1-en-5-one (related); Spiro[cyclopropane-1,3'-indoline], 6'-methoxy-; 1523068-91-8; 6-Methoxy-spiro(cyclopropane-1,3'-indoline)
EINECS	Contact for details

Quality Control

Our 6-Methoxyspiro[Cyclopropane-1,3-Indoline] is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at 2-8°C under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.