Description

3-Bromo-4-Chloro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research for creating libraries of drug candidates.
• Agrochemical Synthesis: Serves as a versatile precursor in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro functional groups.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination, enabling the construction of diverse biaryl structures.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Bromo-4-Chloro-5-Nitrobenzoic Acid
CAS No.	1523065-07-7
Molecular Formula	C7H3BrClNO4
Molecular Weight	280.46 g/mol
Synonyms	Benzoic acid, 3-bromo-4-chloro-5-nitro-; 4-Chloro-3-bromo-5-nitrobenzoic acid; 5-Nitro-3-bromo-4-chlorobenzoic acid; 3-Bromo-4-chloro-5-nitro-benzoic acid; 1523065-07-7 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-5-Nitrobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.