Description

6-Bromo-3-Cyano-2-Fluorobenzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique halogenated and nitrile-substituted benzoic acid structure, which enables precise molecular modifications in complex organic syntheses. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen and fluorine substitution for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromo and fluoro groups are critical for target binding and environmental persistence.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and organic semiconductors, where its electronic properties are advantageous.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	6-Bromo-3-Cyano-2-Fluorobenzoic Acid
CAS No.	1518865-77-4
Molecular Formula	C8H3BrFNO2
Molecular Weight	244.02 g/mol
Synonyms	2-Fluoro-6-bromo-3-cyanobenzoic Acid; 3-Cyano-2-fluoro-6-bromobenzoic Acid; 6-Bromo-2-fluoro-3-cyanobenzoic Acid; Benzoic acid, 6-bromo-3-cyano-2-fluoro-; 1518865-77-4; 6-Bromo-3-cyano-2-fluorobenzoic acid; 2-Fluoro-6-bromo-3-cyanobenzoic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Cyano-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.