Description

Chloro{2-[1-(n-Methoxy)Iminoethyl]Phenyl}{[1,3-Bis(2,6-Di-I-Propylphenyl]Imidzole-2-Ylidene}Palladium(II) is a highly specialized, air-stable palladium N-heterocyclic carbene (NHC) complex designed for demanding cross-coupling catalysis. This compound matters because it offers superior thermal stability and catalytic activity compared to many traditional phosphine-based catalysts, enabling more efficient and robust synthetic transformations. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing and scaling up key synthetic steps, such as Suzuki-Miyaura and Buchwald-Hartwig amination reactions.

Application

This advanced palladium catalyst is engineered for high-performance applications in organic synthesis, particularly where standard catalysts fail due to harsh conditions or demanding substrates.

• Pharmaceutical Intermediate Synthesis: A key catalyst for constructing complex carbon-carbon and carbon-heteroatom bonds in active pharmaceutical ingredient (API) development.
• Agrochemical Manufacturing: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring robust cross-coupling steps.
• Suzuki-Miyaura Cross-Coupling: Enables the coupling of aryl/vinyl boronic acids with aryl/vinyl halides under challenging conditions.
• Buchwald-Hartwig Amination: Catalyzes the coupling of amines with aryl halides for C-N bond formation in drug discovery.
• Material Science Research: Facilitates the synthesis of conjugated polymers, organic semiconductors, and liquid crystals.
• Process Chemistry & Scale-Up: Valued for its stability and consistent performance in moving reactions from lab bench to pilot plant.

Basic Information

Product Name	Chloro{2-[1-(n-Methoxy)Iminoethyl]Phenyl}{[1,3-Bis(2,6-Di-I-Propylphenyl]Imidzole-2-Ylidene}Palladium(II)
CAS No.	1511859-41-8
Molecular Formula	C34H41ClN2O2Pd
Molecular Weight	659.55 g/mol
Synonyms	Palladium(II) Chloro(1-((2,6-diisopropylphenyl)imidazol-2-ylidene)-3-((2,6-diisopropylphenyl)imidazol-2-ylidene)propan-2-one)(2-(1-(methoxyimino)ethyl)phenyl); (SIPr)Pd(Cl)(2-(1-(Methoxyimino)ethyl)Phenyl); Palladium NHC Complex with α-Imino Ligand; Chloro[2-(1-methoxyiminoethyl)phenyl][1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene]palladium; NHC-Pd Catalyst 1511859-41-8; IPr* Palladium Catalyst; Palladacycle Precatalyst.
EINECS	Contact for details

Quality Control

Our production of this high-value catalyst adheres to stringent quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis including HPLC for purity, NMR for structural confirmation, and ICP-MS for precise palladium content and heavy metal screening. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical parameters. We support compliance with cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere (argon or nitrogen) when opening to prevent decomposition. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Palladium Content (ICP-MS)	15.5 - 16.5 %
Heavy Metals (ICP-MS)	≤ 50 ppm
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.