Description

(2,2-Difluoroethyl)Hydrazine Hydrochloride is a high-purity, organofluorine building block essential for advanced synthetic chemistry. This compound serves as a critical precursor for introducing the difluoroethylhydrazine moiety into complex molecular architectures, enabling the development of novel active ingredients. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of new chemical entities, including potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting metabolic diseases and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators that incorporate fluorine for enhanced efficacy and environmental profile.
• Fluorinated Compound Synthesis: Serves as a versatile reagent for introducing the -NH-NH-CH2-CF2H functional group into heterocycles and other complex organic molecules.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and affinity labels for studying enzyme mechanisms and protein interactions.
• Material Science Precursor: Potential use in the synthesis of fluorinated polymers and advanced materials with unique surface properties.

Basic Information

Product Name	(2,2-Difluoroethyl)Hydrazine Hydrochloride
CAS No.	1504582-53-9
Molecular Formula	C2H7ClF2N2
Molecular Weight	132.54 g/mol
Synonyms	2,2-Difluoroethylhydrazine hydrochloride; 1-(2,2-Difluoroethyl)hydrazine hydrochloride; (2,2-Difluoroethyl)hydrazine HCl; Hydrazine, (2,2-difluoroethyl)-, hydrochloride; 2,2-Difluoroethan-1-ylhydrazine hydrochloride; N-(2,2-Difluoroethyl)hydrazine hydrochloride; 1504582-53-9
EINECS	Contact for details

Quality Control

Our (2,2-Difluoroethyl)Hydrazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including NMR, HPLC, and Karl Fischer titration. We adhere to cGMP principles for pharmaceutical intermediates, and our quality commitment extends to full traceability and regulatory support documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.