Description

3,3-Difluoro-1-Methylpiperidin-4-Ol Hydrochloride is a high-purity, fluorinated piperidine derivative supplied as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis, enabling the introduction of a difluorinated heterocyclic moiety. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the difluoro motif for enhanced bioactivity and stability.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology: Employed as a probe or ligand in the study of biological systems and enzyme inhibition.
• Material Science: Potential precursor for specialty chemicals and advanced materials requiring fluorinated heterocycles.

Basic Information

Product Name	3,3-Difluoro-1-Methylpiperidin-4-Ol Hydrochloride
CAS No.	1504212-61-6
Molecular Formula	C7H14ClF2NO
Molecular Weight	201.64 g/mol
Synonyms	1-Methyl-3,3-difluoropiperidin-4-ol hydrochloride; 3,3-Difluoro-1-methyl-4-piperidinol hydrochloride; 4-Piperidinol, 3,3-difluoro-1-methyl-, hydrochloride; 3,3-Difluoro-1-methylpiperidin-4-ol HCl; 1504212-61-6; 1-Methyl-3,3-difluoro-4-hydroxypiperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3,3-Difluoro-1-Methylpiperidin-4-Ol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.