Description

7-Thia-2-Aza-Spiro[3.5]Nonane 7,7-Dioxide Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic sulfonamide-oxalate salt structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Protease Inhibitor Research: Used in the development of novel inhibitors for various protease enzymes.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries for high-throughput screening (HTS).
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of APIs.
• Academic Research: Utilized in universities and research institutes for studying spirocyclic compound chemistry and bioactivity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Product Name	7-Thia-2-Aza-Spiro[3.5]Nonane 7,7-Dioxide Hemioxalate
CAS No.	1501856-47-8
Molecular Formula	C9H13NO7S
Molecular Weight	279.27 g/mol
Synonyms	7-Thia-2-azaspiro[3.5]nonane 7,7-dioxide hemioxalate; 2-Aza-7-thiaspiro[3.5]nonane 7,7-dioxide hemioxalate; Spiro[3.5]nonane-7-thia-2-aza-7,7-dioxide hemioxalate; 1-Oxa-4-azaspiro[4.4]nonane-4-sulfonic acid, oxalate salt; 7-Thia-2-azaspiro[3.5]nonane 7,7-dioxide, compound with oxalic acid (1:0.5); CAS 1501856-47-8
EINECS	Contact for details

Quality Control

Our 7-Thia-2-Aza-Spiro[3.5]Nonane 7,7-Dioxide Hemioxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.