Description

Boc-3-Azido-Ala-OH (Dicyclohexylammonium) Salt is a protected amino acid derivative featuring an azido functional group, supplied as a stable dicyclohexylammonium salt. This compound is a critical building block in peptide synthesis and bioorthogonal chemistry, enabling the site-specific introduction of functional handles via click chemistry reactions. It is primarily utilized by researchers and manufacturers in pharmaceutical development, proteomics, and the synthesis of novel bioconjugates and drug delivery systems.

Application

• Peptide Synthesis: Serves as a key intermediate for incorporating azido-modified alanine residues into peptide chains for subsequent functionalization.
• Bioorthogonal Labeling: The azide group enables efficient, selective conjugation with alkynes via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC) for labeling biomolecules.
• Chemical Biology Probes: Used in the development of activity-based probes and affinity tags for studying protein function and interactions.
• ADC (Antibody-Drug Conjugate) Development: Facilitates the construction of stable, defined linker-payload attachments in next-generation biotherapeutics.
• Material Science: Employed in the surface functionalization of polymers and nanoparticles to create bioactive materials.
• Glycopeptide & Glycoprotein Mimetics: Acts as a scaffold for synthesizing azido-sugar containing peptide mimics.

Basic Information

Product Name	Boc-3-Azido-Ala-OH (Dicyclohexylammonium) Salt
CAS No.	1485525-45-8
Molecular Formula	C20H37N5O4
Molecular Weight	411.54 g/mol
Synonyms	Boc-3-Azido-L-alanine DCHA Salt; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-azidopropanoic acid compound with N,N-dicyclohexylamine; N-α-Boc-3-azido-L-alanine dicyclohexylammonium salt; Boc-Azidoalanine-OH DCHA salt; Boc-L-3-Azidoalanine Dicyclohexylamine Salt; tert-Butyloxycarbonyl-3-azido-L-alanine dicyclohexylammonium salt; Azidoalanine Boc derivative DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-3-Azido-Ala-OH (Dicyclohexylammonium) Salt is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.