Description

1-[4-(Trifluoromethoxy)Phenyl]Propan-1-Amine Hydrochloride is a high-purity organic intermediate featuring a trifluoromethoxy phenyl group, a valuable structural motif in modern chemical synthesis. This compound is critical for research and development in advanced pharmaceutical and agrochemical applications, where its unique fluorinated aromatic system can impart desirable metabolic stability and bioavailability to target molecules. It is primarily sought by process chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced biological activity.
• Ligand & Catalyst Development: Serves as a precursor for chiral amines and ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: A monomer or functionalization agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical research and diagnostic assay development.

Basic Information

Product Name	1-[4-(Trifluoromethoxy)Phenyl]Propan-1-Amine Hydrochloride
CAS No.	1476729-66-4
Molecular Formula	C10H12F3NO•HCl
Molecular Weight	255.66 g/mol
Synonyms	1-(4-(Trifluoromethoxy)phenyl)propan-1-amine hydrochloride; 1-[4-(Trifluoromethoxy)phenyl]propylamine hydrochloride; α-Methyl-4-(trifluoromethoxy)benzenethanamine hydrochloride; 4-(Trifluoromethoxy)amphetamine hydrochloride; 1-(4-Trifluoromethoxyphenyl)propylamine HCl; TFMPA HCl; 1-Amino-1-(4-trifluoromethoxyphenyl)propane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethoxy)Phenyl]Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.