Description

(1R,3S,5R,7R,8As)-7-Ethylhexahydro-1-(6-Hydroxy-4-Quinolinyl)-3,7-Methano-1H-Pyrrolo[2,1-C][1,4]Oxazine is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its precise molecular architecture, which is essential for constructing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Chemical Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for studying complex heterocyclic synthesis and reaction mechanisms.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and development services for client projects.

Basic Information

Product Name	(1R,3S,5R,7R,8As)-7-Ethylhexahydro-1-(6-Hydroxy-4-Quinolinyl)-3,7-Methano-1H-Pyrrolo[2,1-C][1,4]Oxazine
CAS No.	1476067-44-3
Molecular Formula	C19H24N2O2
Molecular Weight	312.41 g/mol
Synonyms	7-Ethylhexahydro-1-(6-hydroxy-4-quinolyl)-3,7-methano-1H-pyrrolo[2,1-c][1,4]oxazine; (1R,3S,5R,7R,8As)-rel-7-Ethylhexahydro-1-(6-hydroxy-4-quinolinyl)-3,7-methano-1H-pyrrolo[2,1-c][1,4]oxazine; Hexahydro-7-ethyl-1-(6-hydroxy-4-quinolinyl)-3,7-methano-1H-pyrrolo[2,1-c][1,4]oxazine; CAS 1476067-44-3
EINECS	Contact for details

Quality Control

Every batch of our (1R,3S,5R,7R,8As)-7-Ethylhexahydro-1-(6-Hydroxy-4-Quinolinyl)-3,7-Methano-1H-Pyrrolo[2,1-C][1,4]Oxazine undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to support pharmaceutical R&D and pre-clinical development requirements. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods, and impurity profiles is provided with each shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.