Description

Brettphos Pd G3 CAS NO 1470372-59-8 is a highly active, second-generation palladium precatalyst featuring the sterically demanding and electron-rich BrettPhos ligand. This compound matters because it offers superior performance in challenging cross-coupling reactions, enabling efficient synthesis of complex molecules under mild conditions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and robust catalytic systems for constructing carbon-heteroatom and carbon-carbon bonds.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling steps in API development.
• Agrochemical Manufacturing: Catalyzing the formation of aryl ethers and amines for novel crop protection agents.
• Materials Science Research: Facilitating the polymerization and functionalization of organic electronic materials.
• Academic & Process Chemistry: Serving as a preferred precatalyst for method development and scaling challenging transformations.
• Fine Chemical Production: Used in the synthesis of specialty chemicals, flavors, and fragrances requiring selective coupling.

Basic Information

Product Name	Brettphos Pd G3
CAS No.	1470372-59-8
Molecular Formula	C₄₅H₆₀NO₃PPd
Molecular Weight	824.30 g/mol
Synonyms	BrettPhos Palladacycle Gen. 3; Chloro(2-dicyclohexylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Pd-PEPPSI-IPent(An)Cl; Palladium(II) BrettPhos precatalyst; Pd G3 BrettPhos; BrettPhos Pd Precatalyst; Palladium complex with BrettPhos ligand
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards for high-purity organometallic catalysts. Each lot is characterized to confirm identity, purity, and catalytic activity. Certificates of Analysis (COA) detailing comprehensive analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep the container sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to orange-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.