Description

(S)-6-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block to introduce stereochemical complexity into target molecules.
• Reference Standard: Used as an analytical standard for method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Potential use in probing enzyme mechanisms or receptor binding studies due to its specific stereochemistry and functional groups.

Basic Information

Product Name	(S)-6-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride
CAS No.	1466429-22-0
Molecular Formula	C9H11BrClN
Molecular Weight	248.55 g/mol
Synonyms	(1S)-6-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride; (S)-6-Bromoindan-1-amine hydrochloride; (S)-1-Amino-6-bromoindane hydrochloride; 6-Bromo-(1S)-indan-1-amine hydrochloride; (S)-6-Bromo-1-indanamine hydrochloride; (1S)-6-Bromo-2,3-dihydro-1H-inden-1-amine HCl; 1466429-22-0; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (S)-6-Bromo-2,3-Dihydro-1H-Inden-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.