Description

2-(Trifluoromethyl)Quinolin-3-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold substituted with a trifluoromethyl group and an amine functionality. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a key building block. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the biological activity of the quinoline core.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or emissive layer materials in electronic displays and lighting.
• Material Science Research: Employed in the development of novel organic semiconductors, ligands for catalysis, and metal-organic frameworks (MOFs).
• Fluorescent Probe & Dye Synthesis: Utilized as a starting material for creating specialized fluorescent markers and dyes used in biochemical assays and imaging.

Basic Information

Product Name	2-(Trifluoromethyl)Quinolin-3-Amine
CAS No.	1464091-60-8
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	3-Amino-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-3-quinolinamine; Quinolin-3-amine, 2-(trifluoromethyl)-; 2-Trifluoromethylquinolin-3-ylamine; 2-Trifluoromethyl-3-aminoquinoline; 1464091-60-8; 3-Amino-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Quinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.