Description

Methyl-3-Amino-2,3-Dihydro-1H-Indene-1-Carboxylate Hydrochloride is a high-purity, synthetically valuable chiral building block and pharmaceutical intermediate. Its significance lies in its fused indane-carboxylate structure, which serves as a privileged scaffold for medicinal chemistry, enabling the development of novel bioactive compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the pharmacokinetic properties of lead compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides with enhanced efficacy and selectivity.
• Asymmetric Synthesis: Utilized in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity for advanced material science.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Methyl-3-Amino-2,3-Dihydro-1H-Indene-1-Carboxylate Hydrochloride
CAS No.	1461708-99-5
Molecular Formula	C12H16ClNO2
Molecular Weight	241.71 g/mol
Synonyms	Methyl 3-amino-2,3-dihydro-1H-indene-1-carboxylate hydrochloride; 1H-Indene-1-carboxylic acid, 3-amino-2,3-dihydro-, methyl ester, hydrochloride; Methyl 3-aminoindane-1-carboxylate hydrochloride; 3-Amino-2,3-dihydro-1H-indene-1-carboxylic acid methyl ester hydrochloride; (1R,3S)-Methyl 3-amino-2,3-dihydro-1H-indene-1-carboxylate hydrochloride (for enantiopure form); (1S,3R)-Methyl 3-amino-2,3-dihydro-1H-indene-1-carboxylate hydrochloride (for enantiopure form)
EINECS	Contact for details

Quality Control

Our Methyl-3-Amino-2,3-Dihydro-1H-Indene-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, chiral analysis, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.