Description

Galnac Beta(1-3)Glcnac-β-Pnp is a specialized synthetic glycoside, specifically a p-nitrophenyl (PNP) glycoside derivative of a GalNAc-β(1-3)-GlcNAc disaccharide. This compound serves as a critical enzymatic substrate for the study and characterization of glycosyltransferases, glycosidases, and other carbohydrate-active enzymes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in glycobiology, drug discovery, and diagnostic assay development.

Application

• Enzyme Kinetics & Characterization: As a chromogenic substrate for high-throughput screening and kinetic analysis of β-glycosidases and specific glycosyltransferases.
• Glycobiology Research: Tool for investigating biosynthetic pathways, enzyme specificity, and inhibition studies in complex carbohydrate synthesis.
• Diagnostic Reagent Development: Key component in developing enzymatic assays for clinical diagnostics and biochemical detection kits.
• Pharmaceutical R&D: Used in drug discovery programs targeting carbohydrate-processing enzymes for therapeutic intervention in cancers, infectious diseases, and metabolic disorders.
• Biocatalyst Screening: Substrate for identifying and engineering novel enzymes for synthetic carbohydrate chemistry and biomanufacturing.
• Academic Research: Fundamental studies on carbohydrate-protein interactions, cell surface recognition, and signal transduction mechanisms.

Basic Information

Product Name	Galnac Beta(1-3)Glcnac-β-Pnp
CAS No.	1456553-26-6
Molecular Formula	C25H34N2O17
Molecular Weight	634.55 g/mol
Synonyms	p-Nitrophenyl N-acetyl-β-D-galactosaminyl-(1→3)-N-acetyl-β-D-glucosaminide; GalNAc-β-(1-3)-GlcNAc-β-PNP; PNP-β-GalNAc-(1-3)-GlcNAc; 4-Nitrophenyl 2-acetamido-2-deoxy-3-O-(2-acetamido-2-deoxy-β-D-galactopyranosyl)-β-D-glucopyranoside; Galβ1-3GlcNAc-β-PNP derivative; Synthetic glycosidase substrate; Chromogenic glycoside substrate; Glycosyltransferase acceptor substrate.
EINECS	Contact for details

Quality Control

Every batch of Galnac Beta(1-3)Glcnac-β-Pnp is produced and analyzed under strict quality protocols to ensure high purity and batch-to-batch consistency, critical for reproducible research results. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.