Description

(S)-S-Ethyl 2-Aminopropanethioate 2,2,2-Trifluoroacetate is a high-purity chiral building block and protected amino acid derivative, essential for advanced organic synthesis. Its primary value lies in providing a stereochemically defined scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is critically needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in protease inhibitor and peptidomimetic drug candidates.
• Peptide Chemistry: Serves as a protected cysteine or cysteine analog precursor in solid-phase and solution-phase peptide synthesis (SPPS).
• Agrochemical Synthesis: Used in the creation of chiral, biologically active compounds for advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Research: Employed in the synthesis of probes and labeled compounds for studying enzyme mechanisms and protein interactions.
• Custom Synthesis: A fundamental building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	(S)-S-Ethyl 2-Aminopropanethioate 2,2,2-Trifluoroacetate
CAS No.	1454706-29-6
Molecular Formula	C7H12F3NO2S
Molecular Weight	231.24 g/mol
Synonyms	(S)-2-Amino-propanethioic acid S-ethyl ester 2,2,2-trifluoroacetate; L-Cysteine S-ethyl ester trifluoroacetate; S-Ethyl (S)-2-aminopropanethioate trifluoroacetate; (S)-S-Ethyl 2-aminopropanethioate TFA salt; (S)-2-(Ethylthio)carbonylamino-propanoic acid trifluoroacetate; TFA salt of (S)-S-Ethyl 2-aminopropanethioate; (S)-Aminoethanethioic acid, S-ethyl ester, 2,2,2-trifluoroacetate
EINECS	Contact for details

Quality Control

Our (S)-S-Ethyl 2-Aminopropanethioate 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.