Description

3-Fluoro-3-Methylbutan-1-Amine Hydrochloride is a high-purity, fluorinated amine hydrochloride salt serving as a critical building block in advanced organic synthesis. Its value lies in providing a structurally unique, fluorine-containing amine moiety that can impart desirable metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis and other specialized organic transformations.
• Peptide Mimetics and Modifications: Incorporated into peptide chains to create analogs with improved stability against enzymatic degradation.
• Material Science Research: Employed in the synthesis of specialty polymers, coatings, or functional materials that benefit from fluorine incorporation.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules to study biological processes and interactions.

Basic Information

Product Name	3-Fluoro-3-Methylbutan-1-Amine Hydrochloride
CAS No.	1454690-47-1
Molecular Formula	C5H13ClFN
Molecular Weight	141.61 g/mol
Synonyms	1-Amino-3-fluoro-3-methylbutane hydrochloride; 3-Fluoro-3-methyl-1-butanamine hydrochloride; 3-Fluoro-3-methylbutylamine hydrochloride; 3-Methyl-3-fluorobutan-1-amine HCl; (3-Fluoro-3-methylbutyl)amine hydrochloride; 3-Fluoro-3-methylbutanamine HCl; 3-Fluoro-3-methylbutan-1-aminium chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-3-Methylbutan-1-Amine Hydrochloride is produced under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each shipment, confirming compliance with customer specifications. Our commitment to quality supports applications in cGMP and other regulated environments where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.