Description

1H-Indene-1,3(2H)-Dione, 5,6-Difluoro- is a high-purity, fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel materials and active pharmaceutical ingredients (APIs), where the introduction of fluorine atoms is critical for modulating biological activity and material properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing novel herbicides and pesticides, where the difluoro-substituted indanedione core can enhance metabolic stability and bioavailability.
• Organic Electronic Materials: Acts as a building block for electron-accepting units in the design of organic semiconductors, OLEDs, and photovoltaic materials.
• Ligand Synthesis: Employed in the preparation of specialized chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe Development: Utilized as a core structure for creating sensitive and selective fluorescent sensors and bio-imaging agents.
• Polymer Chemistry: Incorporated as a monomer or cross-linking agent to impart specific thermal and optical properties to high-performance polymers.

Basic Information

Product Name	1H-Indene-1,3(2H)-Dione, 5,6-Difluoro-
CAS No.	1454686-04-4
Molecular Formula	C9H4F2O2
Molecular Weight	182.13 g/mol
Synonyms	5,6-Difluoro-1H-indene-1,3(2H)-dione; 5,6-Difluoroindane-1,3-dione; 5,6-Difluoro-1,3-indanedione; 5,6-Difluoro-2,3-dihydro-1H-indene-1,3-dione; 1,3-Indanedione, 5,6-difluoro-; Difluoroindanedione; 1454686-04-4 (CAS)
EINECS	Contact for details

Quality Control

Our 1H-Indene-1,3(2H)-Dione, 5,6-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.