Description

2-tert-Butyl 8-Ethyl 6-Thia-2-Azaspiro[3.4]Octane-2,8-Dicarboxylate (Wx102522) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: The spirocyclic structure is valuable for constructing molecules that mimic transition states, relevant for protease inhibitor design.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological processes and target validation.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-tert-Butyl 8-Ethyl 6-Thia-2-Azaspiro[3.4]Octane-2,8-Dicarboxylate (Wx102522)
CAS No.	1453316-13-6
Molecular Formula	C15H25NO4S
Molecular Weight	315.43 g/mol
Synonyms	2-(tert-Butoxycarbonyl)-8-ethoxycarbonyl-6-thia-2-azaspiro[3.4]octane; 2-tert-Butoxycarbonyl-8-ethoxycarbonyl-6-thia-2-azaspiro[3.4]octane; 6-Thia-2-azaspiro[3.4]octane-2,8-dicarboxylic acid, 2-(1,1-dimethylethyl) 8-ethyl ester; WX-102522; Wx102522; AZASPIRO[3.4]OCTANE INTERMEDIATE; tert-Butyl 8-ethyl 6-thia-2-azaspiro[3.4]octane-2,8-dicarboxylate
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 8-Ethyl 6-Thia-2-Azaspiro[3.4]Octane-2,8-Dicarboxylate (Wx102522) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.