Description

tert-Butyl 8-Methoxy-5-Oxa-2-Azaspiro[3.4]Oct-7-Ene-2-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic structure.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Potential precursor for developing new crop protection agents with enhanced biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized compounds for client projects.

Basic Information

Product Name	tert-Butyl 8-Methoxy-5-Oxa-2-Azaspiro[3.4]Oct-7-Ene-2-Carboxylate
CAS No.	1453315-95-1
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	tert-Butyl 8-methoxy-5-oxa-2-azaspiro[3.4]oct-7-ene-2-carboxylate; 2-Azaspiro[3.4]oct-7-ene-2-carboxylic acid, 8-methoxy-5-oxa-, 1,1-dimethylethyl ester; 8-Methoxy-5-oxa-2-azaspiro[3.4]oct-7-ene-2-carboxylic acid tert-butyl ester; Boc-8-Methoxy-5-oxa-2-azaspiro[3.4]oct-7-ene; 1453315-95-1; Spirocyclic oxazolidinone tert-butyl ester; Methoxy-oxa-azaspirooctene carboxylate
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 8-Methoxy-5-Oxa-2-Azaspiro[3.4]Oct-7-Ene-2-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for research and development applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive compound from humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.