Description

tert-Butyl 7-Oxo-5-thia-2-azaspiro[3.4]octane-2-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug molecules, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic and constrained ring system.
• Protease Inhibitor Synthesis: Serves as a precursor in the synthesis of compounds designed to inhibit specific enzymes like proteases.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs).
• Library Synthesis for High-Throughput Screening: Employed to generate diverse chemical libraries for screening against novel biological targets.

Basic Information

Product Name	tert-Butyl 7-Oxo-5-thia-2-azaspiro[3.4]octane-2-carboxylate
CAS No.	1453315-68-8
Molecular Formula	C11H17NO3S
Molecular Weight	243.32 g/mol
Synonyms	2-(tert-Butoxycarbonyl)-7-oxo-5-thia-2-azaspiro[3.4]octane; 2-Boc-7-oxo-5-thia-2-azaspiro[3.4]octane; tert-Butyl 7-oxo-2,5-diazaspiro[3.4]octane-2-carboxylate (related); 5-Thia-2-azaspiro[3.4]octane-2-carboxylic acid, 7-oxo-, 1,1-dimethylethyl ester; Boc-protected spirocyclic thiazolidinone; CAS 1453315-68-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Oxo-5-thia-2-azaspiro[3.4]octane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for advanced research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.