Description

β-D-Glucopyranose, 1-Thio-, 2,3,4,6-Tetraacetate 1-[(1Z)-n-Hydroxy-5-(Methylsulfinyl)Pentanimidate] is a sophisticated, high-purity thioglycoside derivative designed for advanced synthetic chemistry applications. This compound serves as a critical building block for the synthesis of complex bioactive molecules, offering a unique combination of a protected sugar moiety and a functionalized imidate side chain. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutics and chemical probes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel glycosidase inhibitors or glycomimetic drug candidates.
• Chemical Biology Probe Development: Used to create labeled or tagged carbohydrate analogs for studying biological recognition and signaling pathways.
• Glycoconjugate Synthesis: Serves as an activated donor in glycosylation reactions for constructing complex oligosaccharides or glycoconjugates.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical space around sugar-based pharmacophores.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) containing thioglycoside linkages.

Basic Information

Product Name	β-D-Glucopyranose, 1-Thio-, 2,3,4,6-Tetraacetate 1-[(1Z)-n-Hydroxy-5-(Methylsulfinyl)Pentanimidate]
CAS No.	1453081-22-5
Molecular Formula	C20H29NO11S2
Molecular Weight	523.57 g/mol
Synonyms	1-Thio-β-D-glucopyranose 2,3,4,6-tetraacetate 1-[(1Z)-N-hydroxy-5-(methylsulfinyl)pentanimidate]; (1Z)-N-Hydroxy-5-(methylsulfinyl)pentanimidic Acid 1-(2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranosyl) Ester; 2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranose (1Z)-N-hydroxy-5-(methylsulfinyl)pentanimidate; Protected Thioglucose Imidate; Thioglycosyl Donor with Sulfoxide Tail; CAS 1453081-22-5
EINECS	Contact for details

Quality Control

Our β-D-Glucopyranose, 1-Thio-, 2,3,4,6-Tetraacetate 1-[(1Z)-n-Hydroxy-5-(Methylsulfinyl)Pentanimidate] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is moisture-sensitive (hygroscopic) and should be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.