Description

tert-Butyl 2-(5-Bromopyrimidin-2-Yl)Hydrazinecarboxylate is a high-value brominated pyrimidine derivative, serving as a critical protected intermediate in advanced organic synthesis. Its core value lies in enabling the precise construction of complex heterocyclic scaffolds, which are fundamental to modern drug discovery and materials science. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators that require specific pyrimidine-based structures.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or probes to study biological pathways and protein interactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and other functional organic compounds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Used in university and institutional laboratories for methodological development and exploring new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	tert-Butyl 2-(5-Bromopyrimidin-2-Yl)Hydrazinecarboxylate
CAS No.	1452182-34-1
Molecular Formula	C9H13BrN4O2
Molecular Weight	289.13 g/mol
Synonyms	tert-Butyl (5-bromopyrimidin-2-yl)hydrazinecarboxylate; 2-(5-Bromopyrimidin-2-yl)hydrazinecarboxylic acid tert-butyl ester; 1-Boc-2-(5-bromopyrimidin-2-yl)hydrazine; Boc-5-bromo-2-pyrimidylhydrazine; 5-Bromo-2-pyrimidinylhydrazine, N-Boc-protected; 1-(tert-Butoxycarbonyl)-2-(5-bromopyrimidin-2-yl)hydrazine; (5-Bromo-2-pyrimidinyl)hydrazine, N-Boc derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(5-Bromopyrimidin-2-Yl)Hydrazinecarboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.