Description

Jwh 018 n-Propanoic Acid Metabolite is a specific analytical reference standard used for forensic and clinical toxicology. This compound is critical for the accurate identification and quantification of synthetic cannabinoid metabolites in biological matrices. It is primarily required by analytical laboratories, forensic science institutions, and pharmaceutical research organizations engaged in drug metabolism and pharmacokinetic (DMPK) studies.

Application

• Forensic Toxicology Reference Standard: Used as a certified reference material (CRM) for the confirmation of JWH-018 metabolite presence in urine, blood, or hair samples.
• Clinical Research & DMPK Studies: Serves as a key metabolite standard in studies investigating the absorption, distribution, metabolism, and excretion (ADME) of synthetic cannabinoids.
• Method Development & Validation: Essential for developing and validating sensitive analytical methods using LC-MS/MS, GC-MS, or HPLC instrumentation.
• Quality Control & Proficiency Testing: Employed in laboratory QC protocols and external proficiency testing schemes to ensure analytical accuracy and compliance.
• Pharmaceutical Impurity Profiling: Used in research settings to understand and monitor potential metabolite-related impurities.

Basic Information

Product Name	Jwh 018 n-Propanoic Acid Metabolite
CAS No.	1451369-32-6
Molecular Formula	C24H23NO3
Molecular Weight	373.45 g/mol
Synonyms	Naphthalen-1-yl-(1-pentylindol-3-yl)methanone N-Propanoic Acid Metabolite; JWH-018 N-Propanoic Acid; JWH018 Pentanoic Acid Metabolite; 1-Pentyl-3-(1-naphthoyl)indole Carboxy Metabolite; [1-(5-Carboxypentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone; JWH-018 COOH; JWH018 Metabolite I
EINECS	Contact for details

Quality Control

Our reference standards are produced under strict quality-controlled conditions to ensure the highest levels of purity and structural integrity. Each batch is characterized using advanced spectroscopic and chromatographic techniques, including NMR, HRMS, and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation. For short-term use (up to one month), storage at 2-8°C is acceptable.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.