Description

6-Amino-4-Chloroquinazolin-7-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinazoline scaffold. This compound matters for its critical role as a key building block in the synthesis of targeted therapeutic agents, offering researchers and manufacturers precise control over molecular structure. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in developing novel kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for the construction of complex quinazoline-based libraries for drug discovery and lead optimization.
• Biochemical Research: Employed as a reference standard or analytical reagent in proteomics and enzyme inhibition studies.
• Agrochemical Development: Potential use as an intermediate in the research and development of new crop protection agents.

Basic Information

Product Name	6-Amino-4-Chloroquinazolin-7-Ol
CAS No.	1451008-28-8
Molecular Formula	C8H6ClN3O
Molecular Weight	195.61 g/mol
Synonyms	7-Hydroxy-4-chloro-6-aminoquinazoline; 4-Chloro-6-amino-7-hydroxyquinazoline; 6-Amino-4-chloro-7-quinazolinol; 4-Chloro-7-hydroxy-6-quinazolinamine; 1451008-28-8; AQC7-OH; 6-Amino-4-chloro-7(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 6-Amino-4-Chloroquinazolin-7-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.