Description

2-Hydroxy-3-(1H-1,2,4-Triazol-1-Yl)Propanoic Acid is a high-value, functionalized organic acid building block that integrates a triazole heterocycle with a carboxylic acid group. This unique structure makes it a critical intermediate for synthesizing advanced active ingredients, particularly in the agrochemical and pharmaceutical sectors. It is primarily sought after by R&D chemists and process development teams for creating novel compounds with targeted biological activity. The compound, identified by CAS number 1450828-63-3, is supplied to meet the stringent purity and consistency demands of industrial-scale synthesis.

Application

• Agrochemical Intermediate: A key synthon for developing next-generation fungicides, herbicides, and plant growth regulators, leveraging the bioactivity of the 1,2,4-triazole moiety.
• Pharmaceutical Building Block: Used in the research and synthesis of potential drug candidates, including antivirals, antifungals, and enzyme inhibitors.
• Ligand Synthesis: Serves as a precursor for creating complexing agents and chelating ligands in coordination chemistry and catalysis.
• Polymer Modification: Employed to introduce functional groups into polymer chains to alter material properties like hydrophilicity or reactivity.
• Bioconjugation Chemistry: The carboxylic acid group enables coupling reactions for labeling biomolecules or creating peptide mimetics.
• Research & Development: A versatile tool for academic and industrial research in medicinal chemistry and material science.

Basic Information

Item	Detail
Product Name	2-Hydroxy-3-(1H-1,2,4-Triazol-1-Yl)Propanoic Acid
CAS No.	1450828-63-3
Molecular Formula	C5H7N3O3
Molecular Weight	157.13 g/mol
Synonyms	1H-1,2,4-Triazole-1-propanoic acid, 2-hydroxy-; 3-(1H-1,2,4-Triazol-1-yl)-2-hydroxypropanoic acid; 2-Hydroxy-3-(1,2,4-triazol-1-yl)propionic acid; α-Hydroxy-β-(1,2,4-triazol-1-yl)propionic acid; Triazolyl lactic acid; (2-Hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid); 1450828-63-3; 1,2,4-Triazole-1-propanoic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-3-(1H-1,2,4-Triazol-1-Yl)Propanoic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with precise specifications and high purity standards essential for sensitive synthesis. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.