Description

7-Quinazolinol, 4-[(3-Chloro-4-Fluorophenyl)Amino]-6-Nitro- is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists exploring novel kinase inhibitors and targeted cancer therapies. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation oncology treatments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule kinase inhibitors for oncology research.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency and selectivity.
• Preclinical Development: Serves as a precursor for active pharmaceutical ingredients (APIs) in early-stage drug development pipelines.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in HPLC and LC-MS.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies of quinazoline derivatives.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	7-Quinazolinol, 4-[(3-Chloro-4-Fluorophenyl)Amino]-6-Nitro-
CAS No.	1449430-45-8
Molecular Formula	C14H8ClFN4O3
Molecular Weight	334.69 g/mol
Synonyms	4-[(3-Chloro-4-fluorophenyl)amino]-6-nitroquinazolin-7-ol; 6-Nitro-4-((3-chloro-4-fluorophenyl)amino)quinazolin-7-ol; 4-((3-Chloro-4-fluorophenyl)amino)-6-nitro-7-quinazolinol; 7-Hydroxy-4-((3-chloro-4-fluorophenyl)amino)-6-nitroquinazoline; 4-(3-Chloro-4-fluoroanilino)-6-nitro-7-quinazolinol; 6-Nitro-4-(3-chloro-4-fluoroanilino)-7-quinazolinol; Quinazolin-7-ol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitro-
EINECS	Contact for details

Quality Control

Our 7-Quinazolinol, 4-[(3-Chloro-4-Fluorophenyl)Amino]-6-Nitro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed in a desiccated environment when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.