Description

1-(Azetidin-3-Yl)-4-Fluoropiperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique fused azetidine-piperidine scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Employed in the synthesis of potential therapeutics targeting neurological disorders.
• Oncology Research: Serves as a building block for novel small-molecule inhibitors and targeted cancer therapies.
• Chemical Biology: Utilized as a probe or ligand in the study of biological systems and target identification.
• Process Chemistry: Scaled for use in route development and optimization for potential commercial API manufacturing.

Basic Information

Product Name	1-(Azetidin-3-Yl)-4-Fluoropiperidine Hydrochloride
CAS No.	1449117-63-8
Molecular Formula	C8H16ClFN2
Molecular Weight	194.68 g/mol
Synonyms	4-Fluoro-1-(azetidin-3-yl)piperidine hydrochloride; 1-(Azetidin-3-yl)-4-fluoropiperidine HCl; 3-(4-Fluoropiperidin-1-yl)azetidine hydrochloride; Azetidine, 3-(4-fluoropiperidino)-, hydrochloride; 1449117-63-8; 4-Fluoropiperidine-1-carboxylic acid, 3-azetidinyl ester (related); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-(Azetidin-3-Yl)-4-Fluoropiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.