Description

1-(4,6-Dichloro-1,5-Naphthyridin-3-Yl)Ethan-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals. Consistent quality and reliable supply are critical for ensuring the success of downstream R&D and production processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug molecules, especially those targeting infectious diseases or oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex polycyclic compounds due to its reactive dichloro and ketone functional groups.
• Material Science Research: Investigated as a potential monomer or precursor for creating specialized organic electronic materials or ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to service organizations supporting drug discovery and process development projects for global clients.

Basic Information

Product Name	1-(4,6-Dichloro-1,5-Naphthyridin-3-Yl)Ethan-1-One
CAS No.	1448361-59-8
Molecular Formula	C₁₀H₆Cl₂N₂O
Molecular Weight	241.08 g/mol
Synonyms	1-(4,6-Dichloro-1,5-naphthyridin-3-yl)ethanone; 3-Acetyl-4,6-dichloro-1,5-naphthyridine; 4,6-Dichloro-3-acetyl-1,5-naphthyridine; Ethanone, 1-(4,6-dichloro-1,5-naphthyridin-3-yl)-; 1448361-59-8; 1-(4,6-Dichloro-1,5-naphthyridin-3-yl)ethan-1-one (IUPAC)
EINECS	Contact for details

Quality Control

Our 1-(4,6-Dichloro-1,5-Naphthyridin-3-Yl)Ethan-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support our clients' regulatory needs and can supply material suitable for use in GMP-compliant development workflows upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.