Description

3-Bromo-6-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for facilitating complex molecular transformations in advanced synthetic chemistry, offering precise reactivity for constructing sophisticated chemical architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science: Acts as a key monomer or dopant in the creation of organic light-emitting diodes (OLEDs) and other electronic materials due to its electron-deficient quinoline core.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig cross-coupling reactions to form complex biaryl systems.
• Ligand Synthesis: Utilized in the preparation of novel nitrogen-based ligands for catalysis in asymmetric synthesis and transition metal complexes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.

Basic Information

Product Name	3-Bromo-6-(Trifluoromethyl)Quinoline
CAS No.	1447953-13-0
Molecular Formula	C10H5BrF3N
Molecular Weight	276.06 g/mol
Synonyms	3-Bromo-6-(trifluoromethyl)quinoline; Quinoline, 3-bromo-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-3-bromoquinoline; 3-Bromo-6-trifluoromethylquinoline; 1447953-13-0
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.