Description

tert-Butyl 8-Bromoquinolin-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core and carbamate protecting group. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel drug candidates, particularly in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable bromine and carbamate functional groups.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds through cross-coupling and functional group transformation reactions.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Material Science Exploration: Investigated as a component in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	tert-Butyl 8-Bromoquinolin-2-Ylcarbamate
CAS No.	1447608-01-6
Molecular Formula	C₁₄H₁₅BrN₂O₂
Molecular Weight	323.19 g/mol
Synonyms	8-Bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]quinoline; tert-Butyl (8-bromoquinolin-2-yl)carbamate; 2-Quinolinecarboxamide, 8-bromo-N-[(1,1-dimethylethoxy)carbonyl]-; 8-Bromo-N-Boc-quinolin-2-amine; N-Boc-8-bromoquinolin-2-amine; tert-Butyl 8-bromoquinoline-2-carbamate; 1447608-01-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Bromoquinolin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.