Description

tert-Butyl 7-Bromoquinolin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core and carbamate protecting group. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable bromine and carbamate functional groups.
• Kinase Inhibitor Development: Serves as a core scaffold or a critical fragment in the design and synthesis of potential kinase inhibitors.
• Chemical Biology Probes: Utilized in the creation of chemical probes for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects on behalf of biotech and pharma clients.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	tert-Butyl 7-Bromoquinolin-3-Ylcarbamate
CAS No.	1447607-37-5
Molecular Formula	C₁₄H₁₅BrN₂O₂
Molecular Weight	323.19 g/mol
Synonyms	7-Bromo-3-quinolinyl tert-butylcarbamate; tert-Butyl (7-bromoquinolin-3-yl)carbamate; 7-Bromoquinolin-3-yl tert-butylcarbamate; Carbamic acid, N-(7-bromo-3-quinolyl)-, 1,1-dimethylethyl ester; tert-Butyl 7-bromoquinoline-3-carbamate; 1447607-37-5; tert-Butyl 7-bromo-3-quinolylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Bromoquinolin-3-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.