Description

tert-Butyl 7-Fluoroquinolin-4-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, particularly in the development of novel quinolone-based therapeutics. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel fluoroquinolone antibiotic candidates and other biologically active molecules.
• Medicinal Chemistry Research: Used in research and development (R&D) for structure-activity relationship (SAR) studies and the discovery of new pharmacophores.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes from laboratory to pilot and commercial production scales.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials and commercial APIs.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing.

Basic Information

Product Name	tert-Butyl 7-Fluoroquinolin-4-Ylcarbamate
CAS No.	1447607-36-4
Molecular Formula	C₁₄H₁₅FN₂O₂
Molecular Weight	262.28 g/mol
Synonyms	7-Fluoroquinolin-4-yl tert-butylcarbamate; tert-Butyl (7-fluoro-4-quinolinyl)carbamate; 4-Quinolinecarboxamide, 7-fluoro-N-(1,1-dimethylethyl)-; 1447607-36-4; tert-Butyl N-(7-fluoroquinolin-4-yl)carbamate; 7-Fluoro-4-quinolyl tert-butylcarbamate; tert-Butyl 7-fluoro-4-quinolylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Fluoroquinolin-4-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets stringent specifications for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom synthesis to meet specific purity or packaging requirements is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.