Description

tert-Butyl 8-(Trifluoromethyl)Quinolin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold and trifluoromethyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced metabolic stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a precursor for novel pesticides and herbicides, leveraging the biological activity of the quinoline moiety.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme function and biological pathways.
• Material Science: Potential application in the synthesis of specialty chemicals and functional materials due to its fluorinated aromatic structure.
• Process Chemistry Development: Employed in route scouting and optimization for scalable API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	tert-Butyl 8-(Trifluoromethyl)Quinolin-3-Ylcarbamate
CAS No.	1447607-03-5
Molecular Formula	C15H15F3N2O2
Molecular Weight	312.29 g/mol
Synonyms	tert-Butyl N-[8-(trifluoromethyl)quinolin-3-yl]carbamate; 3-Quinolinecarboxamide, N-[8-(trifluoromethyl)-3-quinolinyl]-, 1,1-dimethylethyl ester; 8-(Trifluoromethyl)quinolin-3-amine, N-BOC-protected; BOC-8-Trifluoromethyl-3-aminoquinoline; tert-Butyl (8-(trifluoromethyl)quinolin-3-yl)carbamate; 1447607-03-5; BOC-3-Amino-8-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-(Trifluoromethyl)Quinolin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.