Description

Ethyl 4-Chloro-5-Nitroquinoline-2-Carboxylate is a high-purity, multi-functional quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build novel nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the functionalized quinoline core.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via reactions at the ester, nitro, and chloro substituents, enabling library synthesis for drug discovery.
• Material Science: Investigated as a monomer or precursor for creating specialty polymers and organic electronic materials with unique optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new heterocyclic reaction pathways.

Basic Information

Product Name	Ethyl 4-Chloro-5-Nitroquinoline-2-Carboxylate
CAS No.	1447606-60-1
Molecular Formula	C₁₂H₉ClN₂O₄
Molecular Weight	280.66 g/mol
Synonyms	Ethyl 4-chloro-5-nitroquinoline-2-carboxylate; 2-Quinolinecarboxylic acid, 4-chloro-5-nitro-, ethyl ester; 4-Chloro-5-nitroquinoline-2-carboxylic acid ethyl ester; Ethyl 4-chloro-5-nitro-2-quinolinecarboxylate; 1447606-60-1; UNII-7R6J2Q8N1B; 7R6J2Q8N1B; SCHEMBL23346827; DTXSID60664669
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-5-Nitroquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.