Description

tert-Butyl 4-chloroquinolin-6-ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinoline-based molecular architecture. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and antiviral research pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Item	Detail
Product Name	tert-Butyl 4-Chloroquinolin-6-Ylcarbamate
CAS No.	1447606-50-9
Molecular Formula	C₁₄H₁₅ClN₂O₂
Molecular Weight	278.73 g/mol
Synonyms	6-(((tert-Butoxy)carbonyl)amino)-4-chloroquinoline; 4-Chloro-6-((tert-butoxycarbonyl)amino)quinoline; tert-Butyl (4-chloroquinolin-6-yl)carbamate; 4-Chloro-6-quinolinamine, N-BOC-protected; BOC-4-Chloro-6-aminoquinoline; N-Boc-4-chloro-6-aminoquinoline; 1447606-50-9; 4-Chloro-6-((tert-butoxycarbonyl)amino)quinoline
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-chloroquinolin-6-ylcarbamate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.