Description

(2,4-Difluorobenzyl)Hydrazine Hydrochloride is a high-purity, functionalized hydrazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic and hydrazide/hydrazone moieties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorobenzyl group confers specific biological activity and metabolic stability.
• Heterocyclic Chemistry: Essential for constructing pyrazole, triazole, and other nitrogen-containing heterocycles, which are core structures in many drug candidates.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers and functional materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	(2,4-Difluorobenzyl)Hydrazine Hydrochloride
CAS No.	1446360-19-5
Molecular Formula	C7H9ClF2N2
Molecular Weight	194.61 g/mol
Synonyms	2,4-Difluorobenzylhydrazine Hydrochloride; 1-(2,4-Difluorobenzyl)hydrazine Hydrochloride; (2,4-Difluorophenyl)methanamine Hydrochloride, N-amine; Hydrazine, [(2,4-difluorophenyl)methyl]-, hydrochloride; 2,4-Difluoro-α-hydrazinotoluene Hydrochloride; 2,4-DFBH HCl; 2,4-Difluorobenzyl Hydrazine HCl
EINECS	Contact for details

Quality Control

Our (2,4-Difluorobenzyl)Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.