Description

5-Oxa-2,7-Diazaspiro[3.4]Octan-6-One is a high-value, spirocyclic heterocyclic building block of significant interest in modern medicinal chemistry and pharmaceutical research. Its unique fused ring system containing both oxygen and nitrogen atoms makes it a versatile scaffold for constructing novel bioactive molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule therapeutics targeting a range of diseases.
• Medicinal Chemistry Scaffold: Used in hit-to-lead and lead optimization programs to explore new chemical space and improve drug-like properties such as solubility and metabolic stability.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or core component in the design of bifunctional degrader molecules.
• Agrochemical Research: Employed in the discovery of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe Synthesis: Useful for creating tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects requiring specialized spirocyclic architectures.

Basic Information

Product Name	5-Oxa-2,7-Diazaspiro[3.4]Octan-6-One
CAS No.	1446355-49-2
Molecular Formula	C6H8N2O2
Molecular Weight	140.14 g/mol
Synonyms	5-Oxa-2,7-diazaspiro[3.4]octan-6-one; 2,7-Diazaspiro[3.4]octan-6-one, 5-oxa-; Spiro[3.4]octane-6-one, 5-oxa-2,7-diaza-; 5-Oxa-2,7-diazaspiro[3.4]octan-6-one; 1446355-49-2; 5-Oxa-2,7-diazaspiro[3.4]octane-6-one
EINECS	Contact for details

Quality Control

Every batch of 5-Oxa-2,7-Diazaspiro[3.4]Octan-6-One is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles using techniques such as NMR, HPLC, and MS. Our standard grade meets the stringent requirements for advanced pharmaceutical R&D, and we support custom purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.