Description

4-Bromo-3-Fluoro-6-Nitro-2-(Trifluoromethyl)Phenol, also known as 4-Bromo-6-Nitro-Alpha,Alpha,Alpha,3-Tetrafluoro-o-Cresol, is a high-value, multi-functional fluorinated aromatic building block. This compound is engineered to provide a unique combination of halogen and nitro substituents, making it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated and halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and nitro groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties like chemical resistance or altered refractive index into specialty polymers.
• Dye & Pigment Industry: Employed in the synthesis of complex, high-performance dyes and pigments where halogen and nitro groups are integral to color fastness and molecular structure.
• Chemical Research (R&D): A versatile building block for exploring new chemical reactions and creating libraries of compounds for high-throughput screening in various fields.

Basic Information

Product Name	4-Bromo-3-Fluoro-6-Nitro-2-(Trifluoromethyl)Phenol, 4-Bromo-6-Nitro-Alpha,Alpha,Alpha,3-Tetrafluoro-o-Cresol
CAS No.	1445995-81-2
Molecular Formula	C7H2BrF4NO3
Molecular Weight	303.99 g/mol
Synonyms	4-Bromo-3-fluoro-6-nitro-2-(trifluoromethyl)phenol; 2-Bromo-5-fluoro-6-hydroxy-3-nitrobenzotrifluoride; 4-Bromo-6-nitro-α,α,α,3-tetrafluoro-o-cresol; 2-(Trifluoromethyl)-4-bromo-3-fluoro-6-nitrophenol; o-Cresol, 4-bromo-6-nitro-α,α,α,3-tetrafluoro-; Phenol, 4-bromo-3-fluoro-6-nitro-2-(trifluoromethyl)-; 1445995-81-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoro-6-Nitro-2-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.