Description

Adbrettphos Pd G3 CAS NO 1445972-29-1 is a specialized Buchwald-Hartwig cross-coupling catalyst, specifically a palladium complex of a sterically hindered phosphine ligand. This compound is engineered to deliver superior catalytic activity and selectivity in the formation of carbon-nitrogen and carbon-carbon bonds, which are critical transformations in modern organic synthesis. It is an essential tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to optimize complex coupling reactions.

Application

• Pharmaceutical Intermediate Synthesis: Enabling high-yield, selective amination and arylation reactions for active pharmaceutical ingredient (API) development.
• Agrochemical Manufacturing: Facilitating the synthesis of complex heterocyclic compounds used in crop protection agents.
• Materials Science Research: Catalyzing the polymerization or functionalization of organic electronic materials and polymers.
• Academic & Industrial R&D: Serving as a key reagent for method development and discovery chemistry in cross-coupling reactions.
• Scale-up Process Chemistry: Used in pilot plants and manufacturing for robust, reproducible coupling steps due to its stability and efficiency.
• Ligand Screening & Catalyst Development: Acting as a benchmark or component in studies aimed at developing new catalytic systems.

Basic Information

Item	Details
Product Name	Adbrettphos Pd G3
CAS No.	1445972-29-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Palladium Adbrettphos G3 Catalyst; AdBrettPhos-Pd-G3; Pd(AdBrettPhos) G3; Buchwald Catalyst G3; Palladium complex with 2-(di-tert-butylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl; (2-Biphenyl)di-tert-butylphosphine palladium complex; CataCXium® Pd G3 (related class)
EINECS	Contact for details

Quality Control

Our Adbrettphos Pd G3 is produced under stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized using advanced analytical techniques, including NMR and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and residual solvent content is provided with every shipment, supporting cGMP and ISO 9001 standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or crystalline powder
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Palladium Content	Contact for details
Solubility	Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.