Description

7-Hydroxy-5-Oxo-1,2,3,5-Tetrahydroindolizine-3,8-Dicarboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused indolizine-dicarboxylic acid structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic APIs and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex molecular architectures due to its reactive carboxylic acid and hydroxyl functionalities.
• Biochemical Research: Potential use as a standard or reagent in biochemical assays exploring enzyme inhibition or specific biological pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and high-value organic compounds.

Basic Information

Product Name	7-Hydroxy-5-Oxo-1,2,3,5-Tetrahydroindolizine-3,8-Dicarboxylic Acid
CAS No.	1445865-55-3
Molecular Formula	C10H9NO6
Molecular Weight	239.18 g/mol
Synonyms	1,2,3,5-Tetrahydro-7-hydroxy-5-oxoindolizine-3,8-dicarboxylic acid; 3,8-Indolizinedicarboxylic acid, 1,2,3,5-tetrahydro-7-hydroxy-5-oxo-; 7-Hydroxy-5-oxo-1,2,3,5-tetrahydroindolizine-3,8-dicarboxylic acid; Tetrahydroindolizinedicarboxylic acid derivative; 5-Oxoindolizine-3,8-dicarboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 7-Hydroxy-5-Oxo-1,2,3,5-Tetrahydroindolizine-3,8-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is compatible with strong acid/organic solvent environments but should be kept separate from strong bases and oxidizing agents. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.