Description

3-Quinolinecarboxylic Acid, 7-Bromo-8-Fluoro-4-Hydroxy-, Ethyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical to enable the synthesis of next-generation drug candidates and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated quinoline core.
• Material Science: Serves as a precursor for functionalized organic molecules used in advanced materials, such as organic semiconductors or ligands for catalysis.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tag in the design of chemical probes for studying biological pathways and protein function.
• Academic & Contract Research: Essential for medicinal chemistry programs and synthetic methodology research in university and CRO laboratories worldwide.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-Bromo-8-Fluoro-4-Hydroxy-, Ethyl Ester
CAS No.	1445790-69-1
Molecular Formula	C₁₃H₁₁BrFNO₃
Molecular Weight	328.14 g/mol
Synonyms	7-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 7-bromo-8-fluoro-4-hydroxyquinoline-3-carboxylate; 7-Bromo-8-fluoro-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; 1445790-69-1; 7-Bromo-8-fluoro-4-hydroxy-1H-quinoline-3-carboxylic acid ethyl ester; Quinoline-3-carboxylic acid, 7-bromo-8-fluoro-4-hydroxy-, ethyl ester; 4-Hydroxy-7-bromo-8-fluoroquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 7-Bromo-8-Fluoro-4-Hydroxy-, Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support development and commercial projects requiring material that meets ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.