Description

5-Bromoquinazoline-8-carbonitrile is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of pharmaceutical candidates and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a building block for creating organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in university and CRO laboratories.
• Custom Synthesis: Provides a versatile starting point for contract manufacturing organizations (CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	5-Bromoquinazoline-8-carbonitrile
CAS No.	1445781-40-7
Molecular Formula	C9H4BrN3
Molecular Weight	234.05 g/mol
Synonyms	8-Cyano-5-bromoquinazoline; 5-Bromo-8-cyanoquinazoline; Quinazoline-8-carbonitrile, 5-bromo-; 5-Bromoquinazoline-8-carbonitrile; 1445781-40-7
EINECS	Contact for details

Quality Control

Our 5-Bromoquinazoline-8-carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.