Description

P(o-Tol)3 Pd G3 is a highly active, third-generation palladium precatalyst featuring a tri(o-tolyl)phosphine ligand. This compound matters for its exceptional performance in demanding cross-coupling reactions, offering superior stability and reactivity under mild conditions. It is a critical material for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and efficient catalytic systems for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key carbon-carbon and carbon-heteroatom bond formations in API development.
• Agrochemical Manufacturing: Catalyzing the synthesis of complex active ingredients for crop protection.
• Materials Science Research: Facilitating polymerization and the creation of novel organic electronic materials.
• Cross-Coupling Reactions: Specifically optimized for Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi couplings.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable, robust manufacturing routes.
• Academic & Industrial R&D: A preferred precatalyst for exploring new synthetic methodologies in laboratory settings.

Basic Information

Product Name	P(o-Tol)3 Pd G3
CAS No.	1445086-07-6
Molecular Formula	C21H21P3Pd
Molecular Weight	508.72 g/mol
Synonyms	Tri(o-tolyl)phosphine Palladium G3 Precatalyst; Palladium G3; Pd G3; Pd-P(o-Tol)3 G3; (2-Methylphenyl)diphenylphosphine Palladium Precatalyst; Buchwald Palladium Precatalyst G3; [Pd(μ-Br)(P(o-tolyl)3)]2; Third-Generation Palladium Catalyst
EINECS	Contact for details

Quality Control

Our P(o-Tol)3 Pd G3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistent catalytic performance. A Certificate of Analysis (COA) detailing purity, metal content, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Palladium (Pd) Content	20.0 - 22.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.