Description

Xantphos Pd G3 is a highly active, third-generation palladium catalyst featuring the bulky, electron-rich Xantphos ligand, designed for superior performance in demanding cross-coupling reactions. Its key value lies in enabling efficient and selective transformations under mild conditions, which is critical for streamlining complex synthetic routes in advanced chemical manufacturing. This catalyst is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and robust catalytic systems for constructing carbon-heteroatom and carbon-carbon bonds.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions for active pharmaceutical ingredient (API) development.
• Agrochemical Manufacturing: Facilitating the synthesis of complex molecules for novel herbicides, fungicides, and insecticides.
• Material Science Research: Catalyzing polymerization and polymer functionalization reactions for creating specialty polymers and OLED materials.
• Academic & Industrial R&D: Serving as a premier catalyst for method development and exploring new reaction pathways in organic synthesis.
• Scale-up Process Chemistry: Providing consistent performance and high turnover numbers (TON) for pilot plant and commercial-scale production.
• Fine Chemical Production: Used in the manufacture of complex fragrance, flavor, and dye intermediates.

Basic Information

Product Name	Xantphos Pd G3
CAS No.	1445085-97-1
Molecular Formula	C39H38Cl2P2Pd
Molecular Weight	754.47 g/mol
Synonyms	Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Dichloro[2'-(dicyclohexylphosphino)-2,4,6-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); Xantphos Palladacycle Gen. 3; XPhos Pd G3; Palladium Xantphos Precatalyst; Xantphos-Pd-G3; Buchwald Xantphos Pd G3 Catalyst; Pd(Xantphos) G3
EINECS	Contact for details

Quality Control

Our Xantphos Pd G3 is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high catalytic activity and purity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and compliance with research and industrial application standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic and sensitive to oxidation; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	Yellow to orange-brown solid
Identification (NMR)	Conforms to structure
Assay (Pd content)	≥ 14.0 %
Purity (HPLC)	≥ 95.0 %
Solubility	Soluble in common organic solvents (DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.