Description

Davephos-Pd-G3 is a highly active, third-generation palladium precatalyst featuring a biarylphosphine ligand framework. This compound is engineered to provide exceptional performance in cross-coupling reactions, offering superior stability and reactivity compared to earlier catalyst generations. It is a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and efficient catalytic systems for complex bond formations.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key carbon-carbon and carbon-heteroatom bond-forming steps (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling) in API development.
• Agrochemical Research: Facilitating the synthesis of novel active ingredients through efficient cross-coupling methodologies.
• Polymer & Materials Science: Catalyzing the polymerization or functionalization of monomers to create specialized polymers and electronic materials.
• Academic & Industrial R&D: Serving as a robust and user-friendly catalyst for method development and discovery chemistry in laboratory settings.
• Scale-up Process Chemistry: Providing consistent performance for the transition from milligram to kilogram-scale synthesis in pilot plants.

Basic Information

Product Name	Davephos-Pd-G3
CAS No.	1445085-87-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	DavePhos Pd G3; Palladium DavePhos G3 Precatalyst; Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Pd-PEPPSI-IPent(Cl) related complex; Biarylphosphine-Pd G3 catalyst; Third-generation Buchwald precatalyst; Pd(DavePhos) G3
EINECS	Contact for details

Quality Control

Our Davephos-Pd-G3 is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot is analyzed to confirm identity, purity, and performance in standard coupling reactions. A comprehensive Certificate of Analysis (COA) detailing assay results, impurity profiles, and relevant analytical data (e.g., NMR, HPLC) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use.

Specification

Item	Specification
Appearance	Orange to brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	Contact for details
Solubility	Soluble in common organic solvents (e.g., THF, DCM, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.