Description

Sphos Pd G3 CAS NO 1445085-82-4 is a highly active, third-generation palladium catalyst featuring the bulky, electron-rich SPhos ligand, designed for superior performance in demanding cross-coupling reactions. This catalyst matters because it offers exceptional stability and reactivity, enabling efficient synthesis of complex molecules under mild conditions with high turnover numbers. It is an essential tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and scalable catalytic solutions.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions for API development.
• Agrochemical Production: Facilitating the construction of biaryl and heteroaryl structures found in modern active ingredients.
• Materials Science Research: Catalyzing C-C and C-N bond formations in the creation of novel polymers, ligands, and organic electronic materials.
• Process Chemistry & Scale-up: Ideal for optimizing and scaling coupling reactions from lab to pilot plant due to its robustness.
• Academic & Industrial R&D: A preferred catalyst for methodological development in synthetic organic chemistry.
• Fine Chemical Manufacturing: Used in the production of specialty chemicals requiring selective cross-coupling steps.

Basic Information

Product Name	Sphos Pd G3
CAS No.	1445085-82-4
Molecular Formula	C₄₄H₅₈O₂P₂Pd
Molecular Weight	787.23 g/mol
Synonyms	Chloro(2-dicyclohexylphosphino-2',6'-diisopropoxy-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Pd-PEPPSI-SPhos; PEPPSI-SPhos Palladium Catalyst; SPhos-Pd-G3; Palladium SPhos PEPPSI complex; [2-(2-Aminoethyl)phenyl]chloro[2-(dicyclohexylphosphino)-2',6'-diisopropoxy-1,1'-biphenyl]palladium(II); Pd-SPhos-G3; Third Generation SPhos Palladium Catalyst
EINECS	Contact for details

Quality Control

Every batch of Sphos Pd G3 is manufactured and tested under strict quality management protocols to ensure consistent, high-performance catalytic activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on purity, metal content, and solvent residues.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. The material is easily oxidized and light-sensitive. Keep the container sealed in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to brown solid
Identification (IR)	Conforms to structure
Assay (Pd Content)	≥ 13.5 %
Purity (HPLC)	≥ 95.0 %
Solvent Residue (GC)	Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.